1) Ruyuan Zhou#, Mengqiu Wang#, Yutong Liu, Yihan Yao, Xiao Li, Ailian Wang, Chen Chen, Qian Zhang, Qirou Wu, Qi Zhang, Dante Neculai, Bing Xia, Jian-Zhong Shao, Xin-Hua Feng, Tingbo Liang, Jian Zou, Xiaojian Wang, and Pinglong Xu*. cGAS-STING-Zyxin signaling controls macrophage residency to mitigate antitumor immunity.TheEMBO Journal, 2024 Sep 20, Online ahead of print. doi: 10.1038/s44318-024-00244-9.(IF: 9.4)
2) Lihong He, Xiaozhen Zhang, Fukang Shi, Hanjia Zhang, Yan Chen, Kang Sun, Hanshen Yang, Jiatao Shi, Zihao Lin, Qingsong Lu, Sicheng Wang, Linyue Liu, Xinyuan Liu, Qingbo Meng, Junmin Huang, Pinglong Xu, Xueli Bai, and Tingbo Liang*. Reprograming immunosuppressive microenvironment by eIF4G1 targeting to eradicate pancreatic ductal adenocarcinoma. Cell Reports Medicine. 2024 Sep, 14:101731. doi: 10.1016/j.xcrm.2024.101731. Online ahead of print. (IF: 11.7)
3) Yuping Zheng#, Jishun Chen#, Vinitha Macwan#, Charneal L Dixon #, Xinran Li, Shengjie Liu, Yuyun Yu, Pinglong Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, and Dante Neculai. S-acylation of ATGL is required for lipid droplet homeostasis in hepatocytes. Nature Metabolism. 2024 Aug, 6(8):1549-1565. doi: 10.1038/s42255-024-01085-w. (IF: 18.9)
4) Xinran Li, Xiao Li, Cong Xiang, Jin Cao, Jiansheng Guo, Shilei Zhu, Jingyi Tan, Lijing Wang, Chun Gao, Shengduo Liu, Lifeng Zhao, Bo Yuan, Pinglong Xu, Bing Yang, Dali Li, Bin Zhao, and Xin-Hua Feng. Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis. Cell Reports, 2024 Sep 24, 43(9):114728. doi: 10.1016/j.celrep.2024.114728. (IF: 7.5)
5) Yutong Liu#, Ailian Wang#, Qian Zhang, Dan Zhang, Chen Chen, Xueqi Xiao, Shasha Chen, Lili Lian, Qin Shen, Zhenmin Le, Shengduo Liu, Tingbo Liang, Qinxiang Zheng, Pinglong Xu*, and Jian Zou*. Microglial cGAS-STING signaling underlies the glaucoma pathogenesis. Proc Natl Acad Sci U S A, 2024, 121(36):e2409493121. doi: 10.1073/pnas.2409493121. (IF: 9.4)
6) An Shao, Lulu Jin, Yanni Ge, Ziqiang Ye, Mingyu Xu, Yifan Zhou, Yingyu Li, Linyan Wang, Pinglong Xu, Kai Jin, Zhengwei Mao, and Juan Ye*. C176-loaded and phosphatidylserine-modified nanoparticles treat retinal neovascularization by promoting M2 macrophage polarization. Bioactive Materials, 2024 Sep, 1; (39):392-405. doi: 10.1016/j.bioactmat.2024.05.038. (IF: 18.9)
7) Chenlei Zheng#, Junli Wang#, Yu Zhou, Yi Duan, Rujia Zheng, Yuting Xie, Xiaobao Wei, Jiangchao Wu, Hang Shen, Mao Ye, Bo Kong, Yun-Hua Liu, Pinglong Xu, Qi Zhang, and Tingbo Liang*. IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling. Cell Reports, 2024 Apr, 10;43(4):114088. doi: 10.1016/j.celrep.2024.114088. (IF: 8.8)
8) Ling-Dong Xu, Fei Zhang, Pinglong Xu, and Yao-Wei Huang*. Cross-species transmission and animal infection model of hepatitis E virus. Microbes and Infection, 2024 Apr 16:105338. doi: 10.1016/j.micinf.2024.105338. (IF: 5.8)
9) Yajuan Jiao, Pengwei Zhao, Ling-Dong Xu, Jia-Qi Yu, Hou-Li Cai, Chong Zhang, Chao Tong, Yong-Le Yang, Pinglong Xu, Qiming Sun, Ning Chen, Bin Wang, and Yao-Wei Huang*. Enteric coronavirus nsp2 is a virulence determinant that recruits NBR1 for autophagic targeting of TBK1 to diminish the innate immune response.Autophagy, 2024 Apr 16:1-18. doi: 10.1080/15548627.2024.2340420. (IF: 13.3)
10) Qirou Wu#, Xiaohong Leng#, Qian Zhang, Yezhang Zhu, Ruyuan Zhou, Yutong Liu, Chen Mei, Dan Zhang, Shengduo Liu, Shasha Chen, Xiaojian Wang, Aifu Lin, Xia Lin, Tingbo Liang, Li Shen*, Xin-Hua Feng*, Bing Xia*, and Pinglong Xu*. IRF3 activates RB to authorize cGAS-STING-induced senescence and mitigate liver fibrosis. Science Advances, 2024 Mar,10(9):eadj2102. doi: 10.1126/sciadv.adj2102. (IF: 14.3)
11) Xinran Li#, Cong Xiang#, Shilei Zhu, Jiansheng Guo, Chang Liu, Ailian Wang, Jin Cao, Yan Lu, Dante Neculai, Pinglong Xu, and Xin-Hua Feng*.SNX8 enables lysosome reformation and reverses lysosomal storage disorder.Nature Communications, 2024 Mar, 15(1):2553. doi: 10.1038/s41467-024-46705-x.(IF: 16.6)
12) Yingfeng Tu, Qin Yang, Min Tang, Li Gao, Yuanhao Wang, Jiuqiang Wang, Zhe Liu, Xiaoyu Li, Lejiao Mao, Rui Zhen Jia, Yuan Wang, Tie-Shan Tang, Pinglong Xu, Yan Liu, Lunzhi Dai, Da Jia*.TBC1D23 mediates Golgi-specific LKB1 signaling.Nature Communications, 2024 Feb, 15(1):1785. doi: 10.1038/s41467-024-46166-2.(IF: 16.6)
13) Ailian Wang#, Chen Chen#, Chen Mei, Shengduo Liu, Cong Xiang, Wen Fang, Fei Zhang, Yifan Xu, Shasha Chen, Qi Zhang, Xueli Bai, Aifu Lin, Dante Neculai, Bing Xia, Cunqi Ye, Jian Zou, Tingbo Liang, Xin-Hua Feng, Xinran Li*, Chengyong Shen*, and Pinglong Xu*. Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders. Nature Cell Biology, 2024 Feb, 26(2):219-234. doi: 10.1038/s41556-023-01339-x. (IF: 21.3)
14) Ning Wang, Yu Jiang, Mengjie Li, Haofei Wang, Jie Pan, Yang Tang, Shaofang Xie, Yunyang Xu, Xu Li, Xuefei Zhou, Pinglong Xu, Wenlong Lin, Xiaojian Wang*. Protein Kinase STK24 Promotes Tumor Immune Evasion via the AKT-PD-L1 Axis. Advanced Science (Weinh). 2024 Mar, 11(12):e2304342. doi: 10.1002/advs.202304342. (IF: 15.1)
15) Mu Xiao, Fei Wang, Nuo Chen, Hanchenxi Zhang, Jin Cao, Yi Yu, Bin Zhao, Junfang Ji, Pinglong Xu, Lei Li, Li Shen, Xia Lin, and Xin-Hua Feng*. Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling. Developmental Cell, 2024 Jan, 59(1):48-63. doi: 10.1016/j.devcel.2023.11.020. (IF: 11.8)
16) Shiying Wu, Pinglong Xu*, Fei Zhang*.Advances in targeted therapy for gastric cancer based on tumor driver genes.Journal of Zhejiang University (Medical Sciences). 2024 Feb, 53(1):73-83. doi: 10.3724/zdxbyxb-2023-0522. (Invited review)
17) Shengduo Liu and Pinglong Xu*. Advancements in tyrosine phosphorylation-mediated regulation of innate nucleic acid sensing. Journal of Zhejiang University (Medical Sciences). 2024 Feb, 53(1):35-46. doi: 10.3724/zdxbyxb-2023-0480. (Invited review)
18) Ling-Dong Xu, Yifan Xu, Fei Zhang, Pinglong Xu*, and Lie Wang*. Research progression on immunological mechanisms of viral hepatitis-induced hepatocellular carcinoma. Journal of Zhejiang University (Medical Sciences). 2024 Feb, 53(1):64-72. doi: 10.3724/zdxbyxb-2023-0481. (Invited review)
19) Qin Shen, Pinglong Xu*, and Chen Mei*. Role of Micronucleus-Activated cGAS-STING Signaling in Antitumor Immunity. Journal of Zhejiang University (Medical Sciences). 2024, Feb, 53(1):25-34. doi: 10.3724/zdxbyxb-2023-0485. (Invited review)
20) Mengqiu Wang, Pinglong Xu*, and Qirou Wu*. Cell-to-Cell Communications of cGAS-STING Signaling in Tumor Immune Microenvironment. Journal of Zhejiang University (Medical Sciences). 2024 Feb, 53(1):15-24. doi: 10.3724/zdxbyxb-2023-0482. (Invited review)
21) Jing Li, Pinglong Xu*, and Shasha Chen*. Research Advancements in Mitochondrial-regulated Antitumor Immunity. Journal of Zhejiang University (Medical Sciences), 2024 Feb, 53(1):1-14. doi: 10.3724/zdxbyxb-2023-0484. (Invited review)
22) Yifan Xu, Chen Chen, Zhiyong Liao,*, and Pinglong Xu*. cGAS-STING signaling in cell death: mechanisms of action and implications in pathologies.European Journal of Immunology, 2023, 53(9):e2350386. doi: 10.1002/eji.202350386. (IF: 6.688) (Invited review)
23) Shasha Chen, Zhiyong Liao *, andPinglong Xu*.Mitochondrial control of innate immune responses. Frontiers in Immunology, 2023, 14:1166214. doi: 10.3389/fimmu. 2023.1166214. (IF: 8.786) (Invited review)
24) Zhuangzhuang Zhao#, Ling-Dong Xu#, Fei Zhang#, Qi-Zhang Liang, Yajuan Jiao, Fang-Shu Shi, Biao He, Pinglong Xu*, and Yao-Wei Huang*. Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis. Journal of Biological Chemistry, 2023, 299(5):104668. doi: 10.1016/j.jbc.2023.104668. (IF: 5.286)
25) Fei Zhang#, Ling-Dong Xu#, Qian Zhang, Ailian Wang, Xinyuan Yu, Shengduo Liu, Chu Chen, Shiying Wu, Jianping Jin, Aifu Lin, Dante Neculai, Bin Zhao, Xin-Hua Feng, Tingbo Liang*, Pinglong Xu*, and Yao-Wei Huang*. Targeting proteostasis of the HEV replicase to combat infection in preclinical models. Journal of Hepatology, 2023, 78(4):704-716. doi: 10.1016/j.jhep.2022.12.010. (IF: 30.08)
26) Bo Yuan#, Jinquan Liu#, Aiping Shi#, Jin Cao, Yi Yu, Yezhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Pinglong Xu, Li Shen, Tingbo Liang, Bin Zhao, Xin-Hua Feng*. HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity. The EMBO Journal, 2023, 42(4):e111549. doi: 10.15252/embj.2022111549. (IF: 13.783)
27) Lijing Wang, Shuchen Gu, Fenfang Chen, Yi Yu, Jin Cao, Xinran Li, Chun Gao, Yanzhen Chen, Shuchong Yuan, Xia Liu, Jun Qin, Bin Zhao, Pinglong Xu, Tingbo Liang, Hongyan Tong, Xia Lin, Xin-Hua Feng*. Imatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia. Signal transduction and targeted therapy, 2023, 8(1):120. doi:10.1038/s41392-023-01327-5. (IF: 38.12)
28) Qirou Wu, Xiaohong Leng, and Pinglong Xu*. Intercellular transmission of cGAS-STING signaling in cancer. Cancer Biology & Medicine, 2023, 20(2):93097. doi: 10.20892/j.issn.2095-3941.2022.0750. (Invited Review) (IF: 5.347)
29) Sujing Shi, Dewei Xu, Shuchen Gu, Ningyi Xu, Pinglong Xu, Jin Cao, Xin-Hua Feng*. Protein tyrosine phosphatase PTPN2 regulates TGF-β signaling through Smad4 dephosphorylation. American Journal of Cancer Research. 2022, 12(12):5516-5531. (IF: 5.942)
30) Chen Chen, and Pinglong Xu*. Cellular functions of cGAS-STING signaling. Trends in Cell Biology, 2023, 33(8):630-648. doi: 10.1016/j.tcb.2022.11.001. (Invited Review). (IF: 20.81)(热点/高被引论文)
31) Qian Zhang#, Shengduo Liu#, Chen-Song Zhang#, Qirou Wu, Ruyuan Zhou, Fansen Meng, Ailian Wang, Fei Zhang, Xiaojian Wang, Jun Huang, Yaowei Huang, Jian Zou, Jun Qin, Tingbo Liang, Xin-Hua Feng, Sheng-Cai Lin, and Pinglong Xu*. AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity. Molecular Cell, 2022, 82(23):4519-4536.e7. doi: 10.1016/j.molcel.2022.10.026. (IF: 19.33)
32) Chengyu Shi, Ying Wang, Minjie Wu, Yu Chen, Fangzhou Liu, Zheyuan Shen, Yiran Wang, Shaofang Xie, Yingying Shen, Lingjie Sang, Zhen Zhang, Zerui Gao, Luojia Yang, Lei Qu, Zuozhen Yang, Xinyu He, Yu Guo, Chenghao Pan, Jinxin Che, Huaiqiang Ju, Jian Liu, Zhijian Cai, Qingfeng Yan, Luyang Yu, Liangjing Wang, Xiaowu Dong, Pinglong Xu, Jianzhong Shao, Yang Liu, Xu Li, Wenqi Wang, Ruhong Zhou, Tianhua Zhou, and Aifu Lin*. Promoting antitumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation. Nature Communications, 2022, 13(1):6951. doi: 10.1038/s41467-022-34346-x. (IF: 17.69)
33) Qian Zhang, Chen Chen, Bing Xia, and Pinglong Xu*. Chemical regulation of the cGAS-STING pathway. Current Opinion in Chemical Biology, 2022, 69:102170. doi: 10.1016/j.cbpa.2022.102170. (IF: 8.822)
34) Chen Chen, and Pinglong Xu*. Activation and pharmacological regulation of inflammasomes. Biomolecules, 2022, 12(7):1005. Doi: 10.3390/biom12071005. (IF: 6.064) (Invited Review)
35) Dan Zhang#, Yutong Liu#, Yezhang Zhu#, Qian Zhang, Hongxing Guan, Shengduo Liu, Shasha Chen, Chen Mei, Chen Chen, Zhiyong Liao, Ying Xi, Songying Ouyang, Xin-Hua Feng, Tingbo Liang*, Li Shen*, and Pinglong Xu*. A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis. Nature Cell Biology, 2022, 24(5):766-782. doi: 10.1038/s41556-022-00894-z. (IF: 28.82) (热点/高被引论文)
Selected by Nature Cell Biologyas a representative publication in “Celebrating 25 years of cell biology”.
Previewed in Nature Cell Biology by Dr. Hetz: A chosen STING with a PERky trail, Nature Cell Biology, 2022, 24(5):602-604.
36)Ling-Dong Xu#, Fei Zhang#, Chu Chen, Lei Peng, Wen-Ting Luo, Ruiai Chen, Pinglong Xu*, Yao-Wei Huang*. Revisiting the Mongolian Gerbil Model for Hepatitis E Virus by Reverse Genetics. Microbiology Spectrum, 2022, 10(2):e0219321. doi: 10.1128/spectrum.02193-21. (IF: 7.171)
37)Fansen Meng#, Zhengyang Yu#, Dan Zhang#, Shasha Chen, Hongxin Guan, Ruyuan Zhou, Qirou Wu, Qian Zhang, Shengduo Liu, Bing Yang, Xiao-Qun Ba, Jing Zhang, Jun Huang, Xueli Bai, Jun Qin, Xin-Hua Feng, Songying Ouyang, Yan J. Zhang, Tingbo Liang* and Pinglong Xu*. Induced phase separation of mutant NF2 imprisons cGAS-STING machinery to abrogate antitumor immunity. Molecular Cell, 2021, 81(20):4147-4164.e7. doi: 10.1016/j.molcel.2020.10.018. (IF: 17.97)
Previewed in Molecular Cell: Interferon induction held captive in tumor cells, Molecular Cell, 2021, 81(20):4109-4110.
Highlighted by Cancer Research as Breaking Insights: Phase separated mutant NF2 promotes immune evasion, Cancer Research, 2021, 81(20):5129.
38)Chun Gao, Jianhua Deng, Hanchenxi Zhang, Xinran Li, Shuchen Gu, Mingjie Zheng, Mei Tang, Yezhang Zhu, Xin Lin, Jianping Jin, Long Zhang, Jun Huang, Jian Zou, Zong-Ping Xia, Pinglong Xu, Li Shen, Bin Zhao, Xin-Hua Feng*. HSPA13 Facilitates NF-kB-mediated Transcription and Attenuates Cell Death Responses in TNFα Signaling. Science Advances, 2021, 7(41):eabh1756. doi: 10.1126/sciadv.abh1756. (IF: 14.14)
39)Qingzhe Wu, Jingxin Guo, Yuning Liu, Qi Zheng, Xiaoling Li, Chuanqiang Wu, Dong Fang, Xin Chen, Liang Ma, Pinglong Xu, Xiaofang Xu, Cheng Liao, Ming Wu, Li Shen, Hai Song*. YAP drives fate conversion and chemoresistance of small cell lung cancer. Science Advances, 2021, 7(40):eabg1850. doi: 10.1126/sciadv.abg1850. (IF: 14.14)
40)Jinquan Liu#, Bo Yuan#, Jin Cao, Hongjie Luo, Shuchen Gu, Mengdi Zhang, Ran Ding, Long Zhang, Fangfang Zhou, Mien-Chie Hung, Pinglong Xu, Xia Lin, Jianping Jin, Xin-Hua Feng*. AMBRA1 Promotes TGFβ Signaling via Nonproteolytic Polyubiquitylation of Smad4. Cancer Research, 2021, 81(19):5007-5020. doi: 10.1158/0008-5472.CAN-21-0431. (IF: 12.7)
41)Ruyuan Zhou#, Qirou Wu#, Mengqiu Wang, Seema Irani, Qian Zhang, Fansen Meng, Shengduo Liu, Fei Zhang, Liming Wu, Xia Lin, Xiaojian Wang, Jian Zou, Hai Song, Jun Qin, Tingbo Liang, Xin-Hua Feng, Yan Jessie Zhang, and Pinglong Xu*. The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration. PLoS Biology, 2021, 19(2):e3001122. doi: 10.1371/journal.pbio.3001122. (IF: 8.029)
42)Qiang Qin, Jianan Shou, Mengjie Li, Meidi Gu, Zhuoxian Meng, Pinglong Xu, Hua Meng and Xiaojian Wang*. Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome. Cell Reports, 2021, 35(8):109161. doi: 10.1016/J.CELREP.2021.109161. (IF: 9.423)
43)Qinlong Hao#, Mingjie Zheng#, Kechao Weng#, Yumei Hao, Yao Zhou, Yuchen Lin, Feng Gao, Ziqi Kou, Shoji Kawamura, Ke Yao, Pinglong Xu, Jinghai Chen, and Jian Zou*. Crumbs proteins stabilize the cone mosaics of photoreceptors and improve vision in zebrafish. Journal of Genetics and Genomics, 2021, 48(1):52-62. doi: 10.1016/J.JGG.2020.12.002. (IF: 5.065)
44)Tian Tian, Min Bu, Xu Chen, Linli Ding, Yulan Yang, Jinhua Han, Xin-Hua Feng, Pinglong Xu, Ting Liu, Songmin Ying, Yang Lei, Qing Li, Jun Huang*. The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability. Molecular Cell, 2021, 81(1):198-211.e6. doi: 10.1016/j.molcel.2020.11.007.(IF: 17.97)
45)Shasha Chen#, Shengduo Liu#, Junxian Wang#, Qirou Wu, Ailian Wang, Hongxin Guan, Qian Zhang, Dan Zhang, Xiaojian Wang, Hai Song, Jun Qin, Jian Zou, Songying Ouyang, Xin-Hua Feng, Tingbo Liang, and Pinglong Xu*. TBK1-mediated DRP1 targeting confers nucleic acid sensing to reprogram mitochondrial dynamics and physiology. Molecular Cell, 2020, 80(5):810-827. doi: 10.1016/j.molcel.2020.10.018. (IF: 17.97)
46)Ling-Dong Xu, Fei Zhang*, Lei Peng, Wen-Ting Luo, Chu Chen, Pinglong Xu*, and Yaowei Huang*. Stable Expression of a Hepatitis E Virus (HEV) RNA Replicon in Two Mammalian Cell Lines to Assess Mechanism of Innate Immunity and Antiviral Response. Frontiers in Microbiology, 2020, 11:603699. doi: 10.3389/FMICB.2020.603699. (IF: 4.235)
47)Miao Tian, Xiumei Wang, Jihong Sun, Wenlong lin, Lumin Chen, Shengduo Liu, Pinglong Xu, Xiujun Cai*, and Xiaojian Wang*. IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin. Nature Communications, 202011(1):5762. doi: 10.1038/s41467-020-19627-7.(IF: 12.121)
48)Yumei Hao, Yao Zhou, Yinhui Yu, Mingjie Zheng, Kechao Weng, Ziqi Kou, Jiancheng Liang, Qian Zhang, Xiajing Tang, Pinglong Xu, Brian A Link, Ke Yao, Jian Zou*. Interplay of MPP5a with Rab11 synergistically builds epithelial apical polarity and zonula adherens. Development, 2020, 147(22):dev.184457. doi: 10.1242/dev.184457. (IF: 5.611)
49)Qian Zhang, Ruyuan Zhou, and Pinglong Xu*. The Hippo-YAP pathway in innate anti-microbial and antitumor immunity. Frontiers in Immunology, 2020, 11:1473. doi: 10.3389/fimmu.2020.01473. (Invited review) (IF: 6.429)
50)Ruyuan Zhou, Qian Zhang, and Pinglong Xu*. TBK1, a central kinase in innate immune sensing of nucleic acids and beyond. Acta Biochim Biophys Sin, 2020, 52(7):757-767. doi: 10.1093/abbs/gmaa051. (Invited review) (IF: 2.836)
51)Shiying Wu#, Qian Zhang#, Fei Zhang#, Fansen Meng, Shengduo Liu, Ruyuan Zhou, Qingzhe Wu, Xinran Li, Li Shen, Jun Huang, Jun Qin, Songying Ouyang, Zongping Xia, Hai Song, Xin-Hua Feng, Jian Zou, and Pinglong Xu*. HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defense and antitumor immunity. Nature Cell Biology, 2019, 21(8):1027-1040. doi: 10.1038/s41556-019-0352z. (IF: 17.728)
Previewed in Nature Cell Biology as News & Views: HER2 joins AKT to inhibit STING immunity, Nature Cell Biology, 2019, 21(8):917-918.
Highlighted by Cancer Discovery as Research Watch: HER2 blocks the cGAS-STING-Mediated Immune Response to DNA damage, Cancer Discovery, 2019, 9(9):117.
Highlighted by Science Signaling as Editor’s Choice: HER2 reduces the STING, Science Signaling, 2019, 12(593):eaay9834.
52)Bo Yuan, Jinquan Liu, Jin Cao, Yi Yu, Sisi Liu, Youqiong Ye, Le Ma, Dewei Xu, Ningyi Xu, Yi Li, Pinglong Xu, Jianping Jin, Jianming Xu, Xi Chen, Xia Lin, and Xin-Hua Feng*. PTPN3 Acts as a Tumor Suppressor and Boosts TGF-β Signaling Independent of its Phosphatase Activity. The EMBO Journal, 2019, 38(14):e99945.(IF: 11.227)
53)Chuantao Fang, Jian Li, Sixian Qi, Yubin Lei, Yan Zeng, Jin Li, Shenglin Huang, Pinglong Xu, Kang Chen, Chen Ding, and Faxing Yu*. An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling. EMBO Reports, 2019, 20(6):e47227.(IF: 8.383)
54)Qianting Zhang#, Mu Xiao#, Shuchen Gu#, Yongxian Xu, Ting Liu, Hao Li, Yi Yu, Lan Qin, Yezhang Zhu, Fenfang Chen, Yulong Wang, Chen Ding, Hongxing Wu, Hongbin Ji, Zhe Chen, Youli Zu, Stephen Malkoski, Yi Li, Tingbo Liang, Junfang Ji, Jun Qin, Pinglong Xu, Bin Zhao, Li Shen, Xia Lin, and Xin-Hua Feng*. ALK phosphorylates SMAD4 on tyrosine to disable TGF-β tumour suppressor functions. Nature Cell Biology,2019, 21(2):179-189. (IF: 17.728)
55)Qiong Zhang, Xu Han, Jinfeng Chen, Xiaomei Xie, Jiafeng Xu, Yang Zhao, Jie Shen, Lin Hu, Pinglong Xu, Hai Song, Long Zhang, Bin Zhao, Ying-Jie Wang, and Zongping Xia*. Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) mediate cell density-dependent proinflammatory responses. Journal of Biological Chemistry, 2018, 293(47):18071-18085. (IF: 4.106)
56)Lin Hu, Jiafeng Xu, Xiaomei Xie, Yiwen Zhou, Panfeng Tao, Haidong Li, Xu Han, Chong Wang, Jian Liu, Pinglong Xu, Dante Neculai, and Zongping Xia. Oligomerization-Primed Coiled-coil Domain Interaction with Ubc13 Confers Processivity to TRAF6 Ubiquitin Ligase Activity. Nature Communications, 2017, 8:814. (IF: 12.124)
57)Yi Yu, Shuchen Gu, Wenjian Li, Chuang Sun, Fenfang Chen, Mu Xiao, Lei Wang, Dewei Xu, Ye Li, Chen Ding, Zongping Xia, Yi Li, Sheng Ye, Pinglong Xu, Bin Zhao, Jun Qin, Ye-Guang Chen, Xia Lin, and Xin-Hua Feng. Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-β signaling. Proc Natl Acad Sci U S A, 2017, 114(38):10113-10118. (IF: 9.661)
58)Shengduo Liu#, Shasha Chen#, Xinran Li, Shiying Wu, Qian Zhang, Qiuheng Jin, Lin Hu, Ruyuan Zhou, Zhengyang Yu, Fansen Meng, Siwen Wang, Yaowei Huang, Sheng Ye, Li Shen, Zongping Xia, Jian Zou, Xin-Hua Feng, and Pinglong Xu*. Lck/Hck/Fgr-mediated tyrosine phosphorylation negatively regulates TBK1 to restrain innate antiviral responses. Cell Host & Microbe, 2017, 21(6):754-768. (IF: 17.872)
59)Qian Zhang#, Fansen Meng#, Shasha Chen, Steven W. Plouffe, Shiying Wu, Shengduo Liu, Xinran Li, Ruyuan Zhou, Junxian Wang, Bin Zhao, Jianming Liu, Jun Qin, Jian Zou, Xin-Hua Feng, Kun-Liang Guan, and Pinglong Xu*. Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature Cell Biology, 2017, 19(4):362-374. doi: 10.1038/ncb3496. (IF: 19.064)
Previewed in Nature Cell Biology as News & Views: Hippo interferes with antiviral defences, Nature Cell Biology, 2017, 19(4): 267-269.
Highlighted by Science Signalingas Editor’s Choice: Hippo-sized antiviral defenses, Science Signaling, 2017, 10(474): eaan4043.
60)Pinglong Xu, Xia Lin, and Xin-Hua Feng*. Posttranslational regulation of Smads. Cold Spring Harbor Perspectives in Biology, 2016, 8(12):a022087.(Invited Review) (IF: 9.173)
61)Weiwen Xiang#, Qian Zhang#, Xia Lin, Shiying Wu, Yao Zhou, Fansen Meng, Yunyun Fan, Mu Xiao, Zongping Xia, Jian Zou, Xin-Hua Feng*, and Pinglong Xu*. PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1.Science Advances, 2016, 2(7):e1501889. (IF: 11.5)
62)Fansen Meng, Ruyuan Zhou, Shiying Wu, Qian Zhang, Qiuheng Jin, Yao Zhou, Steven W. Plouffe, Shengduo Liu, Hai Song, Zongping Xia, Bin Zhao, Sheng Ye, Xin-Hua Feng, Kun-Liang Guan, Jian Zou, and Pinglong Xu*. Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation. Genes & Development, 2016, 30(9):1087-1100. (IF: 10.042)
63)Shuchen Gu, Yanjing Liu, Bowen Zhu, Ke Ding, Tso-Pang Yao, Fenfang Chen, Lixing Zhan, Pinglong Xu, Marcelo Ehrlich, Tingbo Liang, Xia Lin, Xin-Hua Feng*. Loss of alpha-tubulin acetylation is associated with TGF-beta-induced epithelial-mesenchymal transition. Journal of Biological Chemistry, 2016, 291(10):5396-405. (IF: 4.258)
64)Xin-Hua Feng*, Pinglong Xu, and Xia Lin. TGF-β Signaling,Methods in Molecular Biology.2015, Springer Protocols, Humana Press.ISBN: 978-1-4939-2965-8.(Book)
65)Fenfang Chen, Xia Lin, Pinglong Xu, Zhengmao Zhang, Yanzhen Chen, Chao Wang, Jiahuai Han, Bin Zhao, Mu Xiao, Feng X-H*. Nuclear Export of Smads by RanBP3L Regulates BMP Signaling and Mesenchymal Stem Cell Differentiation. Molecular and Cellular Biology, 2015, 35(10):1700-11. (IF: 4.777)
66)Pinglong Xu*,Samantha Bailey-Bucktrout, Ying Xi, Daqi Xu, Dan Du, Qian Zhang, Weiwen Xiang, Jianming Liu, Andrew Melton, Dean Sheppard, Harold A. Chapman, Jeffery A. Bluestone, and Rik Derynck*. Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling.Molecular Cell, 2014, 56(6):723-737. (*, Corresponding authors.) (IF: 14.018)
Previewed in Molecular Cell by Dr. Richard Flavell: Resemble and Inhibit: When RLR Meets TGF-β, Molecular Cell, 2014, 56(6):719-720.
Highlighted by Science Signalingas Editor’s Choice: Enhancing and inhibiting TGF-β signaling in infection, Science Signaling, 2015, 8(359):6549.
67)Pinglong Xu,Jianming Liu, Masayo Yumoto and Rik Derynck*. TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association. ScienceSignaling, 2012, 5(222):ra34. (IF: 6.337)
68)Pinglong Xu, Jianming Liu, and Rik Derynck*. Post-translational regulation of TGF-β receptor and Smad signaling. FEBS Letters, 2012, 586(14):1872-84.(IF: 3.341) Invited review in special issue: Sorting the TGF-β labyrinth.
69)Pinglong Xu and Rik Derynck*. Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation. Molecular Cell, 2010, 37(4):551-66. (IF: 14.194)
Recommended by Faculty of 1000.
70)Cheng Liu#, Pinglong Xu#, Samy Lamouille, Jian Xu, and Rik Derynck*. TACE-mediated ectodomain shedding of the type I TGF-β receptor downregulates TGF-β signaling. Molecular Cell,2009, 35(1):26-36. (#, co-first authors.) (IF: 14.608)
Highlight by Science Signaling as Editor’s Choice: Another TGF-β Desensitization Strategy. Science Signaling, 2009, 2(80): p.ec247.
71)Ping-Long Xu, Yun-Qin Liu, Shi-Fang Shan, Yu-Ying Kong, Qing Zhou, Mei Li, Jian-Ping Ding, You-Hua Xie, and Yuan Wang. Molecular mechanism for the potentiation of the transcriptional activity of human liver receptor homolog 1 by steroid receptor coactivator-1. Molecular Endocrinology, 2004, 18(8):1887-905.(IF: 5.807)
72)Xu Ping-Long, Kong Yu-Ying, Xie You-Hua, and Wang Yuan. Corepressor SMRT specificallyrepresses the transcriptional activity of orphan nuclear receptor hB1F/LRH-1. Acta Biochimica et Biophsica Sinica, 2003, 35(10):897-903. (IF: 3.848)
73)Xu Ping-Long, Shan Shi-Fang, Kong Yu-Ying, Xie You-Hua, and Wang Yuan. Characterization of a strong repression domain in the hinge region of orphan nuclear receptor hB1F/LRH-1. Acta Biochimica et Biophsica Sinica, 2003, 35(10): 909-916.(IF: 3.848)
74)Cheng-Kang Zhang, Wei Lin, Yan-Ning Cai, Ping-Long Xu, Hui Dong, Mei Li, Yu-Ying Kong, Gang Fu, You-Hua Xie, Guyang Matthew Huang, and Yuan Wang. Characterization of the genomic structure and tissue-specific promoter of the human nuclear receptor NR5A2 (hB1F) gene. Gene, 2001, 273(2):239-249.(IF: 3.5)
75)Bao Jin-Ku, Wu Chuan-Fang, Lu Hui, Zhou Hong, Zeng Zhong-Kui, Xu Ping-Long, and Zou Jian. The effect of metal ion and denaturant on conformation and function of Polygonatum cyrtonema Hua. Lectin II. Journal of Sichuan University, 2000, 12(6):112-117.
76)Bao Jin-Ku, Xu Ping-Long, Zhou Hong, Zeng Zhong-Kui, and Zou Jian. The relation between chemical modification tyrosine and biological activity of Polygonatum cyrtonema Hua. Lectin II. Chinese Journal of Biochemistry and Molecular Biology, 2000, 16(1):142-146.